Nasopharyngeal (nay-zoh-fuh-RIN-jee-ul) carcinoma ke kankere e hlahang nasopharynx, e ka morao ho nko ea hau le ka holim'a mokokotlo oa 'metso oa hau.
Nasopharyngeal carcinoma e fumaneha seoelo United States.E etsahala hangata haholo likarolong tse ling tsa lefats'e - haholo-holo Asia Boroa-bochabela.
Nasopharyngeal carcinoma ho thata ho lemoha kapele.Mohlomong ke hobane ha ho bonolo ho hlahloba nasopharynx mme matšoao a nasopharyngeal carcinoma a tšoana le a maemo a mang a tloaelehileng.
Nasopharyngeal carcinoma hangata e hlaha ho batho ba lilemo tse mahareng le ba tsofetseng ba kaholimo ho lilemo tse 40, 'me e na le litšobotsi tse hlakileng tsa tikoloho le tsa lelapa, mme sekhahla sa liketsahalo tsa Guangdong se qala China, e tsejoang hape e le "Mofetše oa Guangdong".
1.Litaelo tsa Tlhahlobo le Kalafo ea Nasopharyngeal carcinoma
Litaelong tsa 2021 bakeng sa Tlhahlobo le Kalafo ea Nasopharyngeal Carcinoma, Mokhatlo oa Chaena oa Clinical Oncology (CSCO) o kenyelelitse mekhoa ea ho lemoha serological ho Sehlopha sa I sa bopaki bakeng sa ho hlahlojoa ha nasopharyngeal carcinoma, 'me a bontša hore motsoako oa EB-VCA-IgA. le li-antibodies tsa EB-NA1-IgA EB-virus li ka eketsa sekhahla sa tlhahlobo ea pele ea nasopharyngeal carcinoma ka makhetlo a 3 (21% ~ 79%) le ho fokotsa kotsi ea lefu ka 88%!The 2019 Expert Consensus on the Clinical Application of Markers for Nasopharyngeal Carcinoma e boetse e bontšitse hore EBV-EA-IgA ke letšoao la tšoaetso ea morao-rao ea EBV kapa ho ata ka mafolofolo ha EBV, ka tekanyo e phahameng ea ho khetheha, 'me hangata e sebelisetsoa ho hlahloba kankere ea nasopharyngeal. le ho hlahlojoa kapele.
Boithuto bona bo bonts'a hore lits'oants'o tse tharo tse kopaneng tsa EBV-VCA-IGA, EBV-EA-IGA le EB-NA1-IgA li koahetse ka botlalo EBV gene spectrum, e ntlafatsang ka nepo kutlo le boits'oaro ba ho lemoha ha nasopharyngeal carcinoma, ho fokotsa ho bonoa, ho netefatsa ho nepahala ha ho bolela esale pele mafu, le ho bolela esale pele ketsahalo ea lefu lilemo tse 5-10 esale pele, e leng se loketseng ho hlahloba kankere ea nasopharyngeal e kholo.
2.VCA-IgA+EA-IgA+NA1-IgA e hlahisoang ke Beijing Beier e ka fana ka protocol ea pele ea ho hlahloba lefu la Nasopharyngeal Carcinoma.
Magnetism particulate immuno chemistry luminescence mokhoa
| Lebitso la Sehlahiswa | Kgutsufatso |
| EB kokoana-hloko VCA-IgA sethibela ho lemoha antibody | EB-VCA-IgA |
| EB kokoana-hloko EA-IgA antibody kit ea ho lemoha | EB-EA-IgA |
| Kokoana-hloko ea EB NA1-IgA antibody kit ea ho lemoha | EB-NA1-IgA |
Mokhoa oa Elisa:
| Lebitso la Sehlahiswa | Kgutsufatso |
| EB kokoana-hloko VCA-IgA Elisa kit | EB-VCA-IgA |
| EB kokoana-hloko EA-IgA Elisa kit | EB-EA-IgA |
| kokoana-hloko ea EB NA1-IgA Elisa kit | EB-NA1-IgA |
3.Tshebetso ea Sehlahisoa
Theko ea tlhahlobo ea VCA-IgA e hlahisoang ke Beijing Beier e ka nka sebaka sa lisebelisoa tse tloaelehileng tsa EU bakeng sa ho lemoha kapele le ho lekola nasopharyngeal carcinoma.
British Medical Journal (BMJ) (impact factor 16.378) ke E 'ngoe ea likoranta tse' nè tse itlhommeng pele tsa bongaka lefatšeng.Ka 2017, sehlopha sa lipatlisiso se ile sa hatisa pampiri ho British Medical Journal (BMJ) "Ho hlahlojoa ha lisebelisoa tse supileng tsa VCA-IgA ELISA bakeng sa ho hlahlojoa ha nasopharyngeal carcinoma Chaena: teko ea ho laola linyeoe".
Ka pampiri ena, bakuli ba 200 ba nang le nasopharyngeal carcinoma (NPC) le 200 e tloaelehileng ea serum ea batho (SYSUCC) ea Sun Yat-sen University Cancer Center e ile ea ithutoa le ho lekoa, le ts'ebetso ea lik'hamphani tsa EB-VCA-IgA (ELISA) tse hlahisoang ke 8. baetsi ba lihlahisoa 'marakeng oa lehae ba ne ba bapisoa le tlhahlobo ea ts'ebetso.Qeto ke hore EBV-VCA-IgA (ELISA) kit e hlahisoang ke Beijing Beier e na le phello e tšoanang ea ho hlahloba EBV-VCA-IgA (ELISA) e hlahisoang ke reagent e tsoang linaheng tse ling Oumeng, le EBV-VCA-IgA (ELISA) Sehlahisoa se hlahisoang ke Beijing Beier se ka nka sebaka sa lisebelisoa tse tsoang kantle ho naha bakeng sa ho lemoha le tlhahlobo ea nasopharyngeal carcinoma.Tlhahisoleseding ea bahlahisi ba marang-rang ba nkileng karolo tekong e bonts'itsoe ho Lethathamo la 1, liphetho tsa liteko li bonts'itsoe ho Lethathamo la 2, 'me liqeto tsa liteko li bonts'itsoe ho Lethathamo la 3.
Sephetho sa Teko
Li-recombinant tse tharo tsa VCA-IgA kits-BB,HA le KSB- li bile le liphello tsa tlhahlobo tse lekanang le tsa lisebelisoa tse tloaelehileng.Li ka nkeloa sebaka bakeng sa lisebelisoa tse tloaelehileng 'me metsoako ea tsona e ka sebelisoa ho lemoha le ho hlahloba pele ho NPC.
Nako ea poso: Feb-23-2023